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AIDS Research Today is a free monthly online journal that collates and summarizes the latest research about AIDS, including details on testing, treatment, prevention, hiv, life expectancy.


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Complementary therapies for the treatment of HIV: in search of the evidence.

Mills E, Wu P, Ernst E

Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, HSC-2C12, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada. millsej@mcmaster.ca

The use of complementary and alternative medicine (CAM) is widespread. Yet, little is known about the evidence supporting its use in HIV/AIDS. We conducted a systematic review of randomized clinical trials assessing the effectiveness of complementary therapies for HIV and HIV-related symptoms. Comprehensive literature searches were performed of seven electronic databases. Data were abstracted independently by two reviewers. Thirty trials met our predefined inclusion/exclusion criteria: 18 trials were of stress management; five of Natural Health Products; four of massage/therapeutic touch; one of acupuncture; two of homeopathy. The trials were published between 1989 and 2003. Most trials were small and of limited methodological rigour. The results suggest that stress management may prove to be an effective way to increase the quality of life. For all other treatments, data are insufficient for demonstrating effectiveness. Despite the widespread use of CAM by people living with HIV/AIDS, the effectiveness of these therapies has not been established. Vis à vis CAM's popularity, the paucity of clinical trials and their low methodological quality are concerning.

Published 22 June 2005 in Int J STD AIDS, 16(6): 395-403.
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AIDS Books

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AIDS and Accusation: Haiti and the Geography of Blame (Comparative Studies of Health Systems and Medical Care)