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Discordant molecular characterization results in a Mycobacterium avium complex strain isolated from an AIDS patient.

Huang TS, Lee SS, Chen YS, Tu HZ, Huang WK, Liu YC

Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan.

This report describes an unusual strain of Mycobacterium avium complex isolated from the sputum of an immunocompromised AIDS patient, which did not react with the MAC probe of the BDProbe Tec system, but was identified as Mycobacterium intracellulare by 16S rRNA gene sequencing. Its PCR restriction-enzyme analysis pattern was compatible with an allelic variant of M. avium. It was scotochromogenic, slow-growing and phenotypically identified as Mycobacterium scrofulaceum. Its clinical significance is not certain.

Published 10 June 2005 in J Med Microbiol, 54: 681-3.
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