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Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS).

Paul SR, Hurford MT, Miettinen MM, Aronoff SC, Delvecchio M, Grewal H, Tuluc M

Department of Pediatrics, Temple University School of Medicine, Philadelphia, Pennsylvania, USA. stephan.paul@tuhs.temple.edu

Polymorphous hemangioendotheliomas (PH) are rare and borderline malignant tumors that are among the wide range of vascular tumors. We report here a 13-year-old male presenting with a history of weight loss, opportunistic infections, and lymphadenopathy. He was determined to be HIV positive and to have acquired immunodeficiency syndrome (AIDS). A biopsy of a femoral node was diagnostic of PH. His systemic lymphadenopathy appeared to resolve with anti-retroviral therapy. This tumor should be considered within the differential diagnoses of pediatric and immunocompromised patients.

Published 15 January 2008 in Pediatr Blood Cancer, 50(3): 663-5.
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